The easiest way is to create an SMTP connector which defines @co2.com as its SMTP address space (the domains it handles email for). The SMTP connector should then be configured to communicate directly with the IP address/internal DNS name of Co2's inbound email servers.
The address you specify must be configured in the routers to route across the VPN, rather than attempt to go out onto the Internet.
More information on SMTP connectors at http://www.amset.info/exch
Note that when you specify the address space for @co2.com, you'll be asked to provide a cost value. This can be any number - but lower is usually better. I'd put '1' or '10' in there. You'll then have to edit the existing SMTP connector, where the Address Spaces tab will have '*' entered (for all other domains). Edit the '*' entry and set a higher cost from the value you entered previously.
Higher Cost = Lower Preference
-Matt
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by: alanhardistyPosted on 2009-08-06 at 13:44:32ID: 25037878
You can create an SMTP connector that sends mail directly to company 2's server (you have not mentioned if they have one - so I am assuming they do) and setup the address space for this connector to only send mail for this domain down this route.
If you send via the IP address as the SmartHost, use [ ] brackets around the IP address to make it work properly.
Info on SMTP connectors - http://support.microsoft.c om/kb/2652 93