I'd been doing some research around this myself. here's some answer I could get so far. There're products in the market that can help you scan the Virtual machines while they're offline (shutdown or powered off), rather than on-line (switched on).
While the VMs are online, you would require the AV installed in each of your clients as you mentioned). However, when the VMs are offline, you could stack them together in file-system (like HyperV, ISO, VirtualPC, VMWare workstation) into a folder based structure and initiate a scan using specially constructud AV software. In case your VMs are ESX images, you could manage them through Virtual Infrastructure Client using resource pools and get them scanned offline through the same/different AV software.
okay, now the most important part. At the moment, only two vendors have these 'specialized AV software' that can support offline VM scans, as far as i know - McAfee and TrendMicro. NOTE: I've used McAfee's software, and not TrendMicro.
If you've any more queries, I would be happy to assit you with as much as i know...
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by: leewPosted on 2009-10-19 at 00:03:33ID: 25603034
You need to understand something - a Virtual Machine is the SAME as a PHYSICAL machine with respect to security. If you want the VM protected, you need to run AV software on it, not the host server (the host server should be protected as well).