it will tell you that you could lose the data, but i have never lost data. just have all files saved to that drive closed and then change drive letters and it should be fine..
Well, the risk of data loss is practically non-existent, but that doesn't tell the whole story.
If all you have on drive E: is a bunch of file shares, then moving the share to drive D: (with the same name) should be sufficient. However, if you've got applications installed on the server that are using files on drive E: (like a SQL Server with it's data files on E:), then the "move" would break those applications. You'd be spending a lot of time poking through the registry hunting for references to E:
So, it kinda depends on what you've got installed...
Yes, you can swap the drive letter in disk managament. Go to disk management. Right click on the dirve letter and choose " Change Driver Letters and Paths" Then click on change and choose your Driver Letter.
If the drive letter you choose is already taken then go to that device that is using that driver letter and change it to something like Z now that driver letter is free, now you choose that driver letter that was taken. And then go back and change Z to whatever you want.
There is a change of data loss but it has not happened to me yet.
You can change it safely using Disk Manager, just right click the partition you want to change and choose the appropriate option in the context menu.
In your case you must change the letter to any other first, for example you can change your CDROM to letter X, then change your second disk to D and finally put E to the CDROM.
There is no risk of data lose or corruption but if you still have doubts you can test using a pen drive or something similar.
All good points above. One other to consider which is similar to graye's point: If you have applications installed and something is actively accessing the drive (such as a service or process), then you will get an error message when trying to change the drive letter of your E: drive. You can "force" the change, but then the E: drive letter will not be available for use for your CD-ROM until you reboot.
Make sure and stop all apps, services, processes, etc. that may be accessing your E: drive before you try and re-letter it.