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They apparently have a tool (http://www.trendmicro.com/ftp/products/tsc/sysclean.com) which cleanses the system and, if what they say about being non-destructive is true, then the .exe files should be restored back to normal.
Because it infects Explorer.exe, obviously cleansing should be done under full DOS which is why the cleanup tool is a .com file. (remember to bin your boot floppy afterwards if using it to boot into DOS).
Check here for details: http://www.trendmicro.com/vinfo/virusencyclo/default5.asp?VName=PE_PARITE.A
This virus is also known by other variants/aliases:
W32.Pinfi (Symantec) Â
W32/Parite-B (Sophos) Â
W32/Parite.B (F-Prot) Â
W32/Parite.B (Panda) Â
W32/Pate.b.tmp (McAffee)
Win32.Parite.b (AVP) Â
Win32.Pinfi.A (CA)
http://vil.nai.com/vil/content/v_99690.htm
Â
check
HKEY_CLASSES_ROOT\ exefile\ shell\ open\ command Registry key. The correct data for the (Default) value should be
 "%1" %*
but it sounds like the virus has ruined you, should backup important files, none that have been infected and format.






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and then follow jaygaz's way to modify the registry.
You may also have an additional registry key:
HKEY_CURRENT_USER\Software
Delete the value "PINF"
Sites keep indicating that this is non-destructive, so once cleaned in Full DOS mode and the registry key removed (along with any actions other web sites may suggest)there is no reason to fear the worst.
Appends itself to Explorer.exe to remain memory-resident.
The virus contains an algorithm to slow the infection, so the virus will only infect a few files at a time.
Creates a temp file in the temporary folder. It will get the temporary folder by using a Windows API. The tempfile this virus creates will always have the following name:
[3 random letters][4 random hexadecimal digits].tmp
The file it creates is a UPX packed executable file. The temporary file will be executed by the virus, and it is this file that will attempt to infect files over network shares.
Maybe the system files are now corrupted beyond fixing, but it's worth a try.

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After using AntiVirus software to "cleanse" a system, always be sure to power off and leave it for a while to let everything drain from RAM memory. Â Don't just reboot as occasionally remnants have been left in memory.
I will leave the following recommendation for this question in the Cleanup topic area:
PAQ - no points refunded
Please leave any comments here within the next seven days.
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paullamhkg
EE Cleanup Volunteer
Operating Systems
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Operating systems perform basic tasks, such as recognizing input from the keyboard, sending output to the display screen, keeping track of files and directories on the disk, and controlling peripheral devices such as disk drives and printers. For large systems, the operating system makes sure that different programs and users running at the same time do not interfere with each other. The operating system is also responsible for security, ensuring that unauthorized users do not access the system. Operating systems provide a software platform on top of which other programs, called application programs, can run.