c# better sleep

I wrote a program that does something every 10 seconds.  I am using a sleep, but the program seems to lock up duding the sleep.  Is there a better way to do this so the program is not locked up and will respond to a button press?  Basically I start the process wiht one button and it loops 1000 times until another button is pressed and a flag is set to false.  Currently I have to keep pressing the stop button since the program seems to lock.

System.Threading.Thread.Sleep(5000);

Thanks

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