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Block outbound port 25 on Cisco Pix 501 to all devices except mail server

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Hi Experts,

Our company has Cisco PIX 501.  My knowledge with Cisco is limited.  What we are trying to do is block outbound port 25 on our network except for our one mail server.  We want to do this to prevent PCs that may be infected with viruses from sending out spam.  This way we know the only PC on our network sending out mail is our mail server.  We would like all other outbound access to remain unaffected.  Is there any way to accomplish this?  On the linksys router we do a deny all smtp, then an allow for the mail server with a higher priority than the deny.  Is there any way to accomplish this?  Thanks for the help.
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