Can the article displayed on a page (menu item) be changed dynamically

Is it possible to change the article display on an "article" type page dynamically in response to an onclick event in an html module?

And a more complicated version of that same question:  Can I do that for the single article displayed on the "Front Page" in response to an onclick event in an html module on that page.  That is - I just want the article to change - not the entire page.

I've been able to "simulate" this by creating a series of article pages that "look like" my front page and are items in a hidden menu.  Each of these "fake" home pages has a different article and I simply use onclick="window.location.href="thefullurlofthepage"  That works - but of course the onmouseover events are also fired because (as long as the mouse stays in position) a new copy of the html module is displayed,  It would be much better if the front page simply loaded a new article in its content space,  Any ideas?