I had a similar problem -- here is the cheat sheet Sophos gave me at the time:
What to do
1.Open Windows Firewall with Advanced Security:
Select Start|Control Panel|Classic View|Administrative Tools.
Change the 'Inbound rules' to enable the following, where present:
Remote Administration (NP-In) Domain
Remote Administration (NP-In) Private
Remote Administration (RPC) Domain
Remote Administration (RPC) Private
Remote Administration (RPC-EPMAP) Domain
Remote Administration (RPC-EPMAP) Private
Note: When installation is complete, you should disable these processes
again.
2.Start the 'Remote registry' service on the Windows Vista or Windows 2008 computer (if it is not currently running), and set it to run automatically:
Right-click the Remote Registry service
Select 'Properties
In the 'Startup type' dropdown menu, select Automatic
Click 'OK'.
3.Then either
Open the Windows Control Panel.
Select User accounts.
Select the admin account.
Select 'Turn User Account Control on or off'.
In the dialog that opens, deselect this option.Note: When installation is complete, you should turn this back on.
or
On the Windows Vista or Windows 2008 computer, open Administrative Tools | Local security policy | Local Policy | Security Options .
There is an option called 'User Account Control: Run all administrators in Admin Approval Mode'. The default is 'Enabled'. Change this to 'Disabled'.
4.Reboot the computer.
5.From Enterprise Console, version 2 or above, deploy to the Windows Vista or Windows 2008 computer, specifying the local administrator credentials.
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by: greegzPosted on 2009-11-05 at 04:20:13ID: 25748661
Hello,
P\setup.ex e and see if that helps.
You can try manual instalation. Check if you have shared folder InterChk (C:\Program Files\Sophos Sweep for NT\InterChk) on your server.
if yes then on your client run \\server_name\InterChk\ESX