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Exchange 2000 won't deliver mail (SMTP - Unable to bind to the destination server in DNS)

Okay, Here is the lowdown...

Exch 2000 isn't letting any emails out... we can get emails in and we can send locally. I can look in the SMTP queue and see all of them just sitting there, with the error Unable to bind to the destination server in DNS. I have tried using a few different DNS servers, with no luck.

The network set up -- Three Servers (Exchange, File Server, SQL Server) sitting behind an ISA Server. I can telnet to port 25 on external servers, so i know that i can get out.

HELP!!!!

Not sure what to do...
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JasonBigham

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you are correct -- I am using DNS and not smarthost.

My Exch and ISA are not on the same machine, but both have DNS server installed.

If i take the dns settings out of the SMTP Virtual Server, then i get the error: The remote server did not respond to a connection attempt.

I believe that i have all of the Mail Server Filters/packets/publishing rules set correctly in ISA, so it is probably a DNS problem? How do i confirm / fix this?

Looks like it's gonna be a late night for me...
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Thanks everyone!!!
Hi All,

I have exactly the same problemI was running MS proxy server and exchange 2000 server with IIS.Suddenly one day my cleints cannot access internet through proxy server.I restarted the IIS and all was OK.After 2 hours my exchange stopped sending any outgoing emails.Incomming is fine and so is the local delivery.In the queue I can see all my mails pending which, after a while says status is retry>if we look at the properties it says unable to bind the destination server to DNS.I reinstalled IIS and then reinstalled exchanges 2000.Still the same problem.im using a smart host!

3 sleepless nights now and any help will be appreciated!!!
Hi,

as posted above the problem is with DNS. in the DNS look in the properites and forwarders. Try a different dns address like freedom 2 surf 192.106.56.6 or 194.106.33.42. it sounds as if your current dns stopped responding hence the lack of internet access and email. (either delete old forwarder or push new ones up in dns properties)

i had exactly the same problem with exchange 2k3 sbs, changed my forwarder bang flowing emails