Here is a list of places you can safely delete temp files:
1. C:\Temp (If it exists)
%User% = All Created Users ***Not including All Users, Default Users,NetworkService,LocalService, or anything similar to QBData, McafeeUser, etc.
2. C:\Documents and Settings\%User%\Application Data\Temp
3. C:\Documents and Settings\%User%\Application Data\Temporary Internet Files\
4. C:\Documents and Settings\%User%\Application Data\Temporary Internet Files\Content.ie5 (For current user, Microsoft hides this folder (Even if showing hidden/system files))
And the next few only if you are not worried about not being able to uninstall windows/microsoft updates!
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