I've been programming MFC full-time for about 5 years.  My main focus has been Windows/MFC GUI-specific issues including Windows printing, customizing standard Windows controls, working with (and sometimes around) MFC architecture.

For the past 4 years, I've been been part of a team developing a large (currently 270K lines) investment management package for financial institutions.  Although the company is based in the Chicago area, I lead a 3-man team from my home in Kansas as well as provide MFC support for the entire development group.