Patching is important.  VERY important.  But quite simply, software is complex.  And sometimes, even testing doesn't catch everything.  This is why *I* don't apply Microsoft patches for a minimum of 10 days (second Friday after patch Tuesday):
https://blogs.msdn.microsoft.com/dotnet/2018/07/20/advisory-on-july-2018-net-framework-updates/

That said, if you have the resources to test your own systems, it's another reason you should be testing patches.  Using a subset of systems, test group, etc.  
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by:John
I agree with Lee in large. I do updates on my machines on Patch Tuesday. Clients follow later as Lee suggests.
Do NOT overlook BIOS in 2018. BIOS, Chipset, Video and Network all need updating and that may kick off even more Windows Updates (I have seen that happen).

And we BOTH agree here:  Update your systems.
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