SPAM solution for R5

I was wondering if anyone out there had any recommendations for SPAM control to be used in a Notes environment.  We are a medium sized company approx 500 users, with one (out of 8) of our servers acting as the main gateway to the SMTP.  Also is it truly advantageous to run a intergrated Lotus Notes SPAM solution on the Notes box, would that not create more overhead and suck up resources, rather than running a solution that goes between the Notes box and the SMTP?  Any advice would be great.  
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I am lazy typing the list but take a look at this thread for more number of options. I heard that Trendmicro seem to be more powerful and kind integrates well with notes
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FYI, Tom Lyne's kSpam tool is the same as the OpenNTF tool.  I contacted Tom some time back, and he was kind enough to donate kSpam as Open Source.
Yes I just wanted to provide alternate link in case..!
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