How can I force PDF files to open in Acrobat reader instead of in Internet Explorer?

I am running Windows 2000 sp 3 and Internet Explorer 6.0 and Adobe Acrobat Reader 5.05.  When I go to an internet site, and click on a link to a PDF, it normally opens in another IE window.  If I close the window with the PDF in it, IE crashes.  I have tried every recommended fix for this problem, including the recommendations given to this same question elsewhere on the site, and what I want to know now is this:  

How do I force a link to a PDF file to open in Acrobat Reader, and not as a plug-in to Internet Explorer?  

I have gone into Acrobat Reader and unchecked the box that says "Display PDF in Browser", but then when I try to open a PDF, all I get is another IE window with a cute little box in the upper right corner like you get when you try to open an object that it can't recognize.  

HELP!
TechGirlAsked:
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Karl Heinz KremerCommented:
The "Display PDF in Browser" should do the trick. Do you have any plug-ins installed in Acrobat?

Have you tried to re-install Acrobat? Did you upgrade to IE6, or what this always on your system?
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TechGirlAuthor Commented:
We don't have any third-party plug-ins installed in Acrobat.  We upgraded to IE6 from 5.5.  What I really don't understand is why I can't get the PDF to open in Acrobat Reader without any IE involvement.  That would solve my problem, at least for now.  
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TechGirlAuthor Commented:
I should note that we upgraded to IE6 a long time ago, and this problem is recent.
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Karl Heinz KremerCommented:
IE is involved, because it has to download the file. Once the file is on the local system, it tries to display it. Because IE has no idea about how to display a PDF document, it hands control over to Acrobat Reader. Acrobat Reader then checks if it's supposed to display the document in the browser, or as a standalone application. At least that's what happens from a very high level. Something goes wrong when IE tries to hand off control to the Reader.

Can you try to upgrade to Adobe Reader 6?
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TechGirlAuthor Commented:
I tried upgrading to Acrobat 6, and that didn't help, but I have good news!

I figured out that a recently installed pop-up manager was causing the problem, and once that little bit of software was removed, the problem resolved itself.  Thanks for responding to my question though!  Experts-exchange is such a great security blanket when I'm in need.  
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Computer101Commented:
PAQed, with points refunded (500)

Computer101
E-E Admin
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