Ok, here goes.
I had Exchange 2003 running smoothly today, and then BAM. All of a sudden, no one can pop there email off of the server(yes I have them popping the email down). Whenever they try to, they get a pop-up asking them for a username and password. Then regardless of the combination, it comes back as invalid.
PS: Also, whenever I restart the server, there is an IIS fault error that comes up.