We've got a lab with a bunch of Cisco Routers. We're currently playing with a simple configuration for testing purposes and installed a few NM-1E Ethernet/AUI ports.
Oddly, when we boot the units the enable light on the NM-1E turns on, then it turns off. The routers do not appear to be aware that the NM-1E's are installed.
The IOS is:
IOS (tM) C2600 Software (C2600-IPBASE-M), Version 12.3(9a), Release Software (fc4)
According to Cisco the cards should just work.