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Also do this<br />
download msconfig from here and dictate the startup programs <br />
<a href="http://www.techadvice.com/win2000/m/msconfig_w2k.htm" rel="ugc">http://www.techadvice.com/win2000/m/msconfig_w2k.htm</a><br />
<br />
open msconfig , go to startup tab and disable all applications except Anti-virus.<br />
restart and then scan for virus and spywares. 
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Also do this
download msconfig from here and dictate the startup programs
http://www.techadvice.com/win2000/m/msconfig_w2k.htm [http://www.techadvice.com/win2000/m/msconfig_w2k.htm]

open msconfig , go to startup tab and disable all applications except Anti-virus.
restart and then scan for virus and spywares.

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I am running a 2000 desktop, in the last couple days it has being running very very very slow, looking at task manager RUNDLL32.EXE is running using a % of 97. It is the only application running, adware and spybot have been ran, still having a very slow response,any ideas next step.
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I am running a 2000 desktop, in the last couple days it has being running very very very slow, looking at task manager RUNDLL32.EXE is running using a % of 97. It is the only application running, adware and spybot have been ran, still having a very slow response,any ideas next step.

RUNDLL32.EXE running a 97% on PC

Windows 2000 is an operating system for use on both client and server computers. It is the successor to Windows NT 4.0, and is the last version of Microsoft Windows to display the "Windows NT" designation. Four editions of Windows 2000 were released (Professional, Server, Advanced Server, and Datacenter Server) that shared a core set of features, including many system utilities such as the Microsoft Management Console. All versions of the operating system support NTFS 3.0, Encrypting File System, as well as basic and dynamic disk storage. The Windows 2000 Server family includes support for Active Directory services, Distributed File System and fault-redundant storage volumes.