Cannot change IE 6.0 Home Page

I cannot change my home page setting in IE 6.0 when booting up normally.  When I boot up in safe mode I can change it.  I have run spybot sd - no immediate threats.  Here is the Hijack This file.  Any hints?

Logfile of HijackThis v1.97.7
Scan saved at 11:00:05 AM, on 11/4/2004
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\csrss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\Program Files\lotus\notes\nslsvice.exe
C:\Program Files\lotus\notes\nsl.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Network Associates\Common Framework\FrameworkService.exe
C:\Program Files\Network Associates\VirusScan\Mcshield.exe
C:\Program Files\Network Associates\VirusScan\VsTskMgr.exe
C:\PROGRA~1\NETWOR~1\COMMON~1\naPrdMgr.exe
C:\Program Files\Common Files\Microsoft Shared\VS7Debug\mdm.exe
C:\WINDOWS\system32\nvsvc32.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\wdfmgr.exe
C:\Program Files\Webroot\Enterprise\CommAgent\CommAgent.exe
C:\Program Files\Webroot\Enterprise\Spy Sweeper\SpySweeper.exe
C:\WINDOWS\System32\wltrysvc.exe
C:\WINDOWS\System32\bcmwltry.exe
C:\WINDOWS\System32\alg.exe
C:\WINDOWS\Explorer.EXE
C:\Program Files\Network Associates\VirusScan\SHSTAT.EXE
C:\Program Files\Network Associates\Common Framework\UpdaterUI.exe
C:\Program Files\Apoint\Apoint.exe
C:\Program Files\Roxio\Easy CD Creator 5\DirectCD\DirectCD.exe
C:\WINDOWS\system32\ctfmon.exe
C:\WINDOWS\system32\DSentry.exe
C:\Program Files\Webroot\Enterprise\Spy Sweeper\SpySweeperTray.exe
C:\Program Files\Apoint\Apntex.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\downloads\hijack_this\HijackThis.exe

O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\Program Files\Spybot - Search & Destroy\SDHelper.dll
O4 - HKLM\..\Run: [ShStatEXE] "C:\Program Files\Network Associates\VirusScan\SHSTAT.EXE" /STANDALONE
O4 - HKLM\..\Run: [McAfeeUpdaterUI] "C:\Program Files\Network Associates\Common Framework\UpdaterUI.exe" /StartedFromRunKey
O4 - HKLM\..\Run: [Apoint] C:\Program Files\Apoint\Apoint.exe
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\system32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [nwiz] nwiz.exe /installquiet
O4 - HKLM\..\Run: [AdaptecDirectCD] "C:\Program Files\Roxio\Easy CD Creator 5\DirectCD\DirectCD.exe"
O4 - HKLM\..\Run: [DVDSentry] C:\WINDOWS\system32\DSentry.exe
O4 - HKLM\..\Run: [Synchronization Manager] %SystemRoot%\system32\mobsync.exe /logon
O4 - HKLM\..\Run: [Webroot Spy Sweeper, Enterprise Edition] C:\Program Files\Webroot\Enterprise\Spy Sweeper\SpySweeperTray.exe
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office10\OSA.EXE
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\Office10\EXCEL.EXE/3000
O9 - Extra button: Messenger (HKLM)
O9 - Extra 'Tools' menuitem: Windows Messenger (HKLM)
O16 - DPF: {3E68E405-C6DE-49FF-83AE-41EE9F4C36CE} (Office Update Installation Engine) - http://office.microsoft.com/officeupdate/content/opuc.cab
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://v5.windowsupdate.microsoft.com/v5consumer/V5Controls/en/x86/client/wuweb_site.cab?1098122289563
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://fpdownload.macromedia.com/pub/shockwave/cabs/flash/swflash.cab
O17 - HKLM\System\CCS\Services\Tcpip\Parameters: Domain = vmasc.odu.edu
O17 - HKLM\Software\..\Telephony: DomainName = vmasc.odu.edu
O17 - HKLM\System\CS1\Services\Tcpip\Parameters: Domain = vmasc.odu.edu