Need to restrict browsers in domain to certain sites

I have about 150 domains (currently in an Excel spreadsheet) that I want to restrict users to system-wide. What's the best way to do this?

1.  Can I import from the above-mentioned spreadhseet?
2.  Is GPO the best way to do this? Anyone got an example?

Much appreciated...

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Do you have any kind of firewall on your network?
Your best bet would be to use a hardware firewall to accomplish this. The next best option would include to use a proxy server to control access.
amacaAuthor Commented:
There's no firewall. Not sure I could get this customer to go that direction...they're thinking more IE Content Advisor.
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amacaAuthor Commented:
Don't understand...the link seems to be to a hardware vendor solution. Although that would solve it, it's not what I'm looking for or able to implement at this time.
If GPO is working correctly at your site, you should be able to go to a group policy and go to User Config>Windows Settings>IE Maintenance>Security>Security Zones Click on the Import the current security zones and privacy settings, then click on modify settings and enter all of your sites.  I don't know of a way to import them.

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You may want to go to Content Ratings instead of Security Zones.  Then import, then the Approved sites tab and enter your web sites and tell them never to allow.
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