Small Web host setup??

I know this question has probably been asked a million times, but I haven't found a good concise answer yet.

I would like to set up a small web server at my company, which currently has 1 Server 2003 box and 1 Exchange Box (also server 2003).  This 3rd machine will be to host a number of small traffic websites and an FTP server.  I am looking for suggestions as to the best network structure for this setup.  All of the existing machines are on a single subnet, and I'd assume that I would want the web server on a different subnet.   I'd like to give a handful of users easy access to the webserver on which they would publish sites.

I have a zillion questions about the way this should work, so first I just think I need to get a generally acceptable network infrastructure in place.  My questions then begin to move toward securing files etc.   Does anyone know of a good resource which shows an acceptable way to set up the subnets etc.  i know i know there also a zillion ways to do this too.  it's why i'm asking.  Many of you have probably set up similar networks and have had pretty good luck doing it a certain way.  That's what I'm looking for!

Thanks in advance for any help you can give!