My firewall is logging frequent attempts by programs on my computer (such as Lotus Notes, Firefox or the Spooler SubSystem App (c:\windows\system32\spoolsv.exe) to communicate with (seemingly random) servers on the internet on port 53. They are not attempting to access the DNS servers configured in my network settings.
Does this mean that I have some sort of infection?
I have scanned my hard disk with several anti-virus and anti-malware programs and have so far discovered nothing ominous.
Is there a way of discovering whether they are doing genuine dns queries or not? I had a quick look at Ethereal for example. Unfortunately with my level of knowledge the output was all greek to me. (Make that ancient greek mixed up with higher, pure mathematics.)