System IO.File not found error

I am trying to run a setup program and am getting an error
System.IO.FileNotFound Exception.  

at System.IO_ERror.WinIoError(Int32 error Code, Stringstr)
at System.IO.FileStream.ctro...........

Can someone tell me why I would be getting this error??? or what to look for??
Who is Participating?

[Product update] Infrastructure Analysis Tool is now available with Business Accounts.Learn More

I wear a lot of hats...

"The solutions and answers provided on Experts Exchange have been extremely helpful to me over the last few years. I wear a lot of hats - Developer, Database Administrator, Help Desk, etc., so I know a lot of things but not a lot about one thing. Experts Exchange gives me answers from people who do know a lot about one thing, in a easy to use platform." -Todd S.

Imports System.IO

If File.Exists(yourfile)Then
'do something  
'do something  
End If

Acc to that it doesnt exist

Experts Exchange Solution brought to you by

Your issues matter to us.

Facing a tech roadblock? Get the help and guidance you need from experienced professionals who care. Ask your question anytime, anywhere, with no hassle.

Start your 7-day free trial
LAppling7775Author Commented:
the error shows the file name and path and the form shows the file - so I am not understanding what it is missing.
LAppling7775Author Commented:
It works on one computer but not on the other - could it be a .net framework issue and if so what would I do???
Become a Microsoft Certified Solutions Expert

This course teaches how to install and configure Windows Server 2012 R2.  It is the first step on your path to becoming a Microsoft Certified Solutions Expert (MCSE).

what file is it looking for?
LAppling7775Author Commented:
Just a regular text file.  
Do you have the same .NET framework installed on each PC? .NET 2.0 programs will not run on 1.1
Are you sure the file is in the same location as the computer the program executes successfully on?
maybe the install deletes the file
What did you find out?
It's more than this solution.Get answers and train to solve all your tech problems - anytime, anywhere.Try it for free Edge Out The Competitionfor your dream job with proven skills and certifications.Get started today Stand Outas the employee with proven skills.Start learning today for free Move Your Career Forwardwith certification training in the latest technologies.Start your trial today
Visual Basic.NET

From novice to tech pro — start learning today.