Something within my SBS domain is enforcing a policy that's disallowing any user (including Domain Admins) with any profile from editing the IE security settings. Additionally, no one can successfully load the CompanyWeb page without being prompted to enter their domain username and password. This is a similar problem to:
Only problem is, this is a different SBS, domain, network etc...
Any ideas? I suspect it's a recent patch for Windows as it's only recently started behaving in this way, except I've not changed the default policies or introduced any new ones!