My browser has recently become infected with some extremely annoying malware/spyware OHPE 4.12_23 that basically states my computer has been infected with spyware pop-up management software.  It is further prompting me to click on the balloon to get information about getting rid of said spyware.  This is outright EXTORTION.  WHat is the best and easiest and efficient way to rid myself of this pest and avoid becoming infected again..?  PLEASE HELP...!  This is sooooooooooo verrrrrrry annoying.

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Will SzymkowskiSenior Solution ArchitectCommented:
Hello there,

what you could and download and I recommend is Ad-aware SE Personal and Spybot Search and Destroy. Here are the Links

Use these programs together and it will get rid of most/all of the spyware and it will also prevent it from coming back.

You can also try Ewido anti-malware.
Download and install the free version of Ewido anti-malware.
Update first then scan in safe mode.

Also download hijackthis

when you have installed this program run it then post your results here

Before running these programs turn off system restore. Do the following

Right Click My Computer
Properties, System Restoe Tab
Put and check mark in the box "Turn Off system restore"

hope this helps
Everythign the Spec01 said. For an online scan you can hit this site (asks for ActiveX install to scan but it's banner/ad/spyware free).

For preventing infection again Spybot has a "tea timer" feature that runs in your sytsem tray and notifies you of any registry change attempts.
Browser Hijack Recover(BHR) would help u a lot. Easy to use. Follow the steps.
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then run
panda active scan @
bitdefender online scan @
kaspersky online scan @

and post a hjt log.
oh before psting the hjt log pls run smitfraud fix in safe mode. And reboot.
Hijackthis(as already suggested) would be the best first option IMHO, it is a very good diagnostic tool which can tell us what malware is present in your system, and we can then tell you the right tool to use instead of trying many different tools to find which one works.
It can tell us whether its smitfraud infection is the one you got or something else.

download HijackThis 1.99.1
Open Hijackthis, click "Do a system scan and save a logfile" don't fix anything yet.
Notepad will also open, copy its contents and paste it to either these sites:
then at the bottom left corner click "paste"
Copy the address/url and post it here:

Or paste the log at --> 
and click "Analyse", click "Save".  Post the link to the saved list here.
in addition,

you can use windows defender, which stays resident in memory, and helps to prevent this kind of thing from happening.

Good Luck,
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