Two factor authentication

I need to set up two factor authentication, presumably with RSA tokens for a small business that is using a Windows XP as a file server. We have some employees that log in remotely over the internet using VPN or a program called Logmein (rmeote access). Will RSA software agents work on a Windows XP computer, and if it does wil there be any problem when more than one user logs in at a time to access files? Obviously Win 2003 would be fine but this is not an option at the moment.
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Rich RumbleConnect With a Mentor Security SamuraiCommented:
Like a smartcard login? There are many smart-cards that work well with M$
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