Exchange 2003 Not Receiving Mail Please help

When sending e-mail from an outside e-mail account I am getting an error message

“Remote host said: 550 5.7.1 Unable to relay for john@parrishclan.com
Giving up on 64.169.41.5.”

This was tested and working only a few weeks ago and now it is not working.  We are running Exchange 2003.  it sits behind an ISA Server and we control the outside DNS for it.  I am really at a lose of words for this one.  Any help would be great on this.

the only errors in the Exchange error log are as follows.

Failed to generate offline Address Book /dc=com/dc=ecsrefining/cn=Configuration/cn=Services/cn=Microsoft Exchange/cn=ECSRefining/cn=Address Lists Container/cn=Offline Address Lists/cn=ParrishClanUsers, error '80072030'

The database "First Storage Group\Public Folder Store (SC20)" has 7 megabytes of free space after online defragmentation has terminated.

not sure if they are related I am totaly new to exchange.  I was recieving the secound error sense I installed it so I am not sure if it means anything because exchange seams to be working fine.  all inside Trafic is working great.

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Iggy79Asked:
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SembeeCommented:
The DNS for that domain is a mess. Whoever manages it needs to take a good look at the configuration of DNS and the servers in general.

You have servers listed in DNS that aren't responding, don't exist...

http://www.dnsreport.com/tools/dnsreport.ch?domain=parrishclan.com

Cannot relay means that Exchange doesn't know it is responsible for that domain. The most common reason is the domain is not listed, or not enabled, in recipient policy. That is the first place to check.
As there is an ISA involved, I would also consider testing SMTP inside using telnet: http://www.amset.info/exchange/telnet-test.asp
If it works inside then the ISA is at fault.

Simon.
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Iggy79Author Commented:
and now I have fixed the offline address book issue as well so I am not logging any error messages for this problem
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Iggy79Author Commented:
Well I fixed it.  Not sure how but I did it.   on a fluke I deleted the Connector and then recreated it again. And then it started to work.  I am guessing something was wrong with the one that was there.  Thanks Sembee for your help again.
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