C# Registry Permission can't Write to Registry

I'm trying to make a program that will write to a particular registry Key that "Everybody" doesn't have full control over.

Here's the basic Gyst of the code:
RegistryKey key2 = Registry.LocalMachine.OpenSubKey("SYSTEM\\CurrentControlSet\\Enum\\FTDIBUS\\VID_0403+PID_6001+5&138461b1&0&1\\0000", true);

This particular key inherits its security settings from the Enum Key.

If I run the same line without the true on the end, it goes past this line, but hangs whenever I try to write to the key.

I can successfully write to other keys/values with no problem.

Here's the kicker. If I go into RegEdit, I can set the permissions manually so that Everyone has Full Access to this key,  the program works without a hitch.

Currently only SYSTEM has Full Access.

I plan on deploying this to many computers, so I need a way for the program to Change the Permissions for that Key. I'm assuming if the person running the program has Admin Access, then I should be able to accomplish this.

I have tried inserting:
[assembly: RegistryPermissionAttribute(SecurityAction.RequestMinimum, Write=@"HKEY_LOCAL_MACHINE\\SYSTEM\\CurrentControlSet\\Enum")]

at the beginning, but that doesn't do anything.

I've fooled with with RegistryAccessRules, and I've made a Rule that will accomplish what I want, but I have no earthly idea how to apply that rule to the registry key if it isn't open in write mode (true at the end);

I would greatly appreciate any help at all with this.