We are running Windows XP Pro SP2 in a Windows 2003 Server environment using AD.
We have group policies for each department. Our customer service department is the most restrictive. Just recently they are getting a warning message about open files when executing various things on their desktop. Unknown Publisher/Unknown File Type and then the local path for the program they are trying to execute. They just click OPEN and the program is available to them. They use about 6-8 programs so they go through this routine on every boot.
Some initial research pointed to issues that occur with network apps but these are all local.
The question is difficult and we are in need so it's worth 500 points and hopefully I have made myself clear.