Can SET22.tmp and *.tmp file be safely removed?

I found severl SETXX.tmp files in my system32 folder. Can I safely remove them? Can I safely remove all *.tmp file from my HD?

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neutron7Connect With a Mentor Commented:
any file with .tmp extention can be safely deleted as long as the program that uses it is not running.
jimmymcp02Connect With a Mentor Commented:
did what neutron7 suggested before you delete the file i would suggest reboot the pc if file remain on system then try deleting the file if you can delete the file try to monitor whats using the file...

neutron7Connect With a Mentor Commented:
look in your temp folder i bet there is a lot of junk in there.

C:\Documents and Settings\username\Local Settings\Temp
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