Get Rid From Systems.exe (16 bit ms-dos subsytem)

systems.exe can be dropped by any worms/trojans in the system.
SDBot/Rbot/IRC trojans also drop this file in the system.
You can either let us look at a hijackthis log to check which causes it, or you can just run SDFix.

Download SDFix and save it to your desktop.
http://downloads.andymanchesta.com/RemovalTools/SDFix.zip

Double click SDFix.exe and it will extract the files to %systemdrive%
(Drive that contains the Windows Directory, typically C:\SDFix)

Please then reboot your computer in Safe Mode by doing the following :

* Restart your computer
* After hearing your computer beep once during startup, but before the Windows icon appears, tap the F8 key continually;
*  Instead of Windows loading as normal, a menu with options should appear;
*  Select the first option, to run Windows in Safe Mode, then press "Enter".
*  Choose your usual account.

*  Open the extracted folder and double click "RunThis.bat" to start the script.
*  Type "Y" to begin the script.
*  It will remove the Trojan Services then make some repairs to the registry and prompt you to press any key to Reboot.
*  Press any Key and it will restart the PC.
*  Your system will take longer that normal to restart as the fixtool will be running and removing files.
*  When the desktop loads the Fixtool will complete the removal and display "Finished", then press any key to end the script and load your desktop icons.
*  Finally open the SDFix folder on your desktop and copy and paste the contents of the results file "Report.txt" back

It could also be the "W32/Agobot-P" an IRC backdoor Trojan and network worm.
c:\windows\systems32\systems.exe <-- this file is bad and needs to be deleted, BUT before deleting, it is better to check to make sure the related registry entry is not being called early at start up. Sometimes deleting a file while reg entry is still present can cause the pc to not boot or user not being able to login.

You could also show us a hijackthis log. To check for relevant reg entries.
http://danborg.org/spy/hjt/alternativ.exe
Open Hijackthis, click "Do a system scan and save a logfile" don't fix anything yet.
Upload the log to EE-stuff.com or to any hosting sites and just post the link here.

KillBox.Net
http://killbox.net/

Just in case the above tools dont help in deleting the file.....
(she is always on the money though, with viral topics...)

Logfile of HijackThis v1.99.1
Scan saved at 08:51:02 &#1576;.&#1592;, on 2007/02/28
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\Explorer.EXE
C:\Program Files\FarStone\VirtualDrive\VDTask.exe
C:\WINDOWS\vcdplayx.exe
C:\Program Files\Conceiva\DownloadStudio\DownloadStudioScheduleMonitor.exe
C:\Program Files\Analog Devices\SoundMAX\SMTray.exe
C:\WINDOWS\system32\Kernel.exe
C:\Program Files\Nero\Nero 7\InCD\InCD.exe
C:\Program Files\DAP\DAP.EXE
C:\Program Files\SlySoft\CloneCD\CloneCDTray.exe
C:\PROGRA~1\SYMANT~1\SYMANT~1\vptray.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\Adobe\Acrobat 6.0\Distillr\acrotray.exe
C:\Program Files\Sony Corporation\Picture Package\Picture Package Menu\SonyTray.exe
C:\Program Files\Symantec_Client_Security\Symantec AntiVirus\DefWatch.exe
C:\Program Files\Nero\Nero 7\InCD\InCDsrv.exe
C:\Program Files\Analog Devices\SoundMAX\SMAgent.exe
C:\WINDOWS\system32\svchost.exe
C:\Program Files\Common Files\Ulead Systems\DVD\ULCDRSvr.exe
C:\Program Files\Microsoft Office\OFFICE11\WINWORD.EXE
C:\Program Files\Internet Explorer\IEXPLORE.EXE
C:\Documents and Settings\assistant\My Documents\My Completed Downloads\hijackthis\HijackThis.exe
C:\WINDOWS\system32\ntvdm.exe

O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 6.0\Acrobat\ActiveX\AcroIEHelper.dll
O2 - BHO: IeMonitor - {8170D7DC-BDD6-461e-88EB-F047257898C9} - C:\Program Files\Conceiva\DownloadStudio\DLMonitr.dll
O2 - BHO: AcroIEToolbarHelper Class - {AE7CD045-E861-484f-8273-0445EE161910} - C:\Program Files\Adobe\Acrobat 6.0\Acrobat\AcroIEFavClient.dll
O3 - Toolbar: &DownloadStudio - {CB789373-04D5-4ef4-9C16-871463FD0830} - C:\Program Files\Conceiva\DownloadStudio\WebDLBar.dll
O3 - Toolbar: Adobe PDF - {47833539-D0C5-4125-9FA8-0819E2EAAC93} - C:\Program Files\Adobe\Acrobat 6.0\Acrobat\AcroIEFavClient.dll
O4 - HKLM\..\Run: [VirtualDrive] "C:\Program Files\FarStone\VirtualDrive\VDTask.exe" /AutoRestore
O4 - HKLM\..\Run: [vcdplayx] "C:\WINDOWS\vcdplayx.exe"
O4 - HKLM\..\Run: [NeroFilterCheck] C:\Program Files\Common Files\Ahead\Lib\NeroCheck.exe
O4 - HKLM\..\Run: [UVS10 Preload] C:\Program Files\Ulead Systems\Ulead VideoStudio 10\uvPL.exe
O4 - HKLM\..\Run: [DownloadStudio] C:\Program Files\Conceiva\DownloadStudio\DownloadStudioScheduleMonitor.exe
O4 - HKLM\..\Run: [Smapp] C:\Program Files\Analog Devices\SoundMAX\SMTray.exe
O4 - HKLM\..\Run: [Babylon Client] C:\Program Files\Babylon\Babylon-Pro\Babylon.exe -AutoStart
O4 - HKLM\..\Run: [Microsoft Windows] C:\WINDOWS\system32\Kernel.exe
O4 - HKLM\..\Run: [InCD] C:\Program Files\Nero\Nero 7\InCD\InCD.exe
O4 - HKLM\..\Run: [DownloadAccelerator] "C:\Program Files\DAP\DAP.EXE" /STARTUP
O4 - HKLM\..\Run: [CloneCDTray] "C:\Program Files\SlySoft\CloneCD\CloneCDTray.exe" /s
O4 - HKLM\..\Run: [vptray] C:\PROGRA~1\SYMANT~1\SYMANT~1\vptray.exe
O4 - HKCU\..\Run: [CTFMON.EXE] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O4 - Global Startup: Acrobat Assistant.lnk = C:\Program Files\Adobe\Acrobat 6.0\Distillr\acrotray.exe
O4 - Global Startup: Adobe Gamma Loader.lnk = C:\Program Files\Common Files\Adobe\Calibration\Adobe Gamma Loader.exe
O4 - Global Startup: Picture Package Menu.lnk = ?
O8 - Extra context menu item: &Clean Traces - C:\Program Files\DAP\Privacy Package\dapcleanerie.htm
O8 - Extra context menu item: &Download with &DAP - C:\Program Files\DAP\dapextie.htm
O8 - Extra context menu item: Add Page To DownloadStudio Scrapbook... - C:\Program Files\Conceiva\DownloadStudio\ds_snap.htm
O8 - Extra context menu item: Download &all with DAP - C:\Program Files\DAP\dapextie2.htm
O8 - Extra context menu item: Download Image Using DownloadStudio... - C:\Program Files\Conceiva\DownloadStudio\ds_img.htm
O8 - Extra context menu item: Download Page Using DownloadStudio... - C:\Program Files\Conceiva\DownloadStudio\ds_all.htm
O8 - Extra context menu item: Download Selection Using DownloadStudio... - C:\Program Files\Conceiva\DownloadStudio\ds_sel.htm
O8 - Extra context menu item: Download Target Using DownloadStudio... - C:\Program Files\Conceiva\DownloadStudio\ds_file.htm
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\OFFICE11\EXCEL.EXE/3000
O8 - Extra context menu item: Show Page Links Using DownloadStudio... - C:\Program Files\Conceiva\DownloadStudio\ds_link.htm
O8 - Extra context menu item: Subscribe To RSS Feed... - C:\Program Files\Conceiva\DownloadStudio\ds_rss.htm
O9 - Extra button: (no name) - {4D0C4820-53F7-4d79-A2E1-5252683CF69C} - C:\Program Files\Conceiva\DownloadStudio\DownloadStudio.exe
O9 - Extra 'Tools' menuitem: &DownloadStudio - {4D0C4820-53F7-4d79-A2E1-5252683CF69C} - C:\Program Files\Conceiva\DownloadStudio\DownloadStudio.exe
O9 - Extra button: DownloadStudio - {7FCA7BD7-8F4D-4a81-BE72-A470F4E517D5} - C:\Program Files\Conceiva\DownloadStudio\WebDLBar.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O17 - HKLM\System\CCS\Services\Tcpip\..\{7E07DF35-0336-4304-9DA0-0E62E1FEF74E}: NameServer = 192.9.9.3,217.218.155.104
O20 - Winlogon Notify: NavLogon - C:\WINDOWS\system32\NavLogon.dll

O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: InCD Helper (InCDsrv) - Nero AG - C:\Program Files\Nero\Nero 7\InCD\InCDsrv.exe
O23 - Service: NBService - Nero AG - C:\Program Files\Nero\Nero 7\Nero BackItUp\NBService.exe
O23 - Service: Remote Packet Capture Protocol v.0 (experimental) (rpcapd) - Unknown owner - %ProgramFiles%\WinPcap\rpcapd.exe" -d -f "%ProgramFiles%\WinPcap\rpcapd.ini (file missing)
O23 - Service: SoundMAX Agent Service (SoundMAX Agent Service (default)) - Analog Devices, Inc. - C:\Program Files\Analog Devices\SoundMAX\SMAgent.exe
O23 - Service: Ulead Burning Helper (UleadBurningHelper) - Ulead Systems, Inc. - C:\Program Files\Common Files\Ulead Systems\DVD\ULCDRSvr.exe