mouse acting strange

I hold down the left mouse button and try to enlarge Word or excel or my browser and it doesn't pull it along.  In Excel when I am trying to choose a bunch of cells by dragging them out, its like I am raising my finger, but I am not.  Its an optical dell mouse.
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Has this problem occured with any other mouse? If you can, try another mouse and see if the problem occurs again. If it does not happen again, there is some faulty hardware in the mouse.
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