VIM question - script to remove 1st two characters from each new line

I am using VIM 7.1 on WXP to make some alterations to a file that is almost 3MB in size.  I did remove all asterisks from the file using a global search and replace (%s/*/ /g), but now I need to remove the first two characters from each new line in the file (beginning at a certain point, because I tried to do a couple hundred lines manually).  Sometimes the first two are blank spaces, sometimes they are some very funky characters.  New lines are showing up as ^M in my file.

Is there a simple script I can write and run to accomplish this?