Citrix Presentation Server 4.5 - .Net application in AIE will only run with Admin rights -" .Net Framework Initialization Error"

Apologies in advance because I'm a self confessed citrix newbie....

I'm currently running a POC using the virtual machine from Citrix of Presentation Server 4.5.

I have one application (it's an in-house .Net app) that won't work straight up, as it writes to the filesystem and registry as part of it operation (and confuses any additionl clients) ... so I'm trying to use the AIE to get it up and running.

I have used both methods (assigning an already installed version to an IE and installing into the IE) and in both cases, the app will not work unless I log in with admin rights.  if I log in a s anything else, I get a .Net framework error:

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XXXXXXX.exe - .NET Framework Initialization Error
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To run this application, you first must install one of the following versions of the ,NET Framework:
v2.0.50727
Contact your application publisher for instructions about obtaining the appropriate version of the .NET Framework.
<OK>
---------------------------------------------------------------------------------------------


The server has the framework installed - and the app will run if not within the isolation environment - it will also run as admin.  I tried changing the NT perms on the AIE tree... HELP!!!!!


One other issue I'm having is trying to assign a set client name to my clients (so they don't end up with WI_xxxxxxxx_. I can do this if I download the ICA and set the client name on here ... can I do this anywhere centrally.