Stuck setting up Veritas Backup Exec Jobs

I have just started using Symantec (formerly Veritas) Backup Exec 10d, and although I know what I want to do, I am stuck on how to get there.
Here is what I am trying to do;
I have 11 Tapes which I have inventoried and labeled as follows:
Monday, Tuesday, Wednesday, Thursday
Weekly 1, Weekly 2, Weekly 3, Weekly 4, Weekly 5
Month End, Quarter End.
Now from here is where it gets hazy for me.  I want to setup my backup jobs to run as you see, Monday on Monday, Tuesday on Tuesday, etc... then Weekly's on Fridays, etc.  Do I create different sets like Daily, and put the MTWT in that set, then a Weekly and put all the Weekly's in that, or should I create one set and work off of that?
Also, should I create only one job for my entire backups which include Exchange, Active Directory, Two File Servers, etc?  Or if I create multiple jobs to run, can I get them to run on the same tape?  

My tape device is a HP LTO Ultrium-2 Drive with 400GB Tapes, which should be plenty for what we are backing up.  Currently we have an online backup that is 300 GB, and this is taking over for that.

Any help would be greatly appreciated.