New harddrive now reads as E instead of C

Just replaced the crashed harddrives in my pc, and put the disk in, after installation the harddrive now reads as drive E instead of C.  Does that matter?  I tried to go to Disk Management and change the letter but it will not let me do it.  Any advise?

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psyclown-Connect With a Mentor Commented:
It shouldn't make any big differents, if you don't have anything on the drive (since its new), unless you have a shortcut to the drive.

Or maybe take a look at this:
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