error when run Websphere App server 6.0

The NoClassDefFoundError: usually contains the name of the class that JVM is unable to find. Could you supply the entire error message which may contain that class name?

I had the same error trying to start Websphere Application Server 6.0 from Eclipse

you may find as I did one or more VM arguments in the arguments tab of the launch configuration properties lack quotes around them.  In my case it was this particular VM argument, which was causing my problem.

"-Xbootclasspath/p:C:/Program Files/IBM/WebSphere/AppServer/java/jre/lib/ext/ibmorb.jar;C:/Program Files/IBM/WebSphere/AppServer/java/jre/lib/ext/ibmext.jar -Xms50m -Xmx256m" 

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eclipse-server-launchconfigurati.txt

The only difference being that your original doesn't include double quotes around this portion:

-Xbootclasspath/p:C:/Program Files/IBM/WebSphere/AppServer/java/jre/lib/ext/ibmorb.jar;C:/Program Files/IBM/WebSphere/AppServer/java/jre/lib/ext/ibmext.jar -Xms50m -Xmx256m

and the "corrected one" does.

Interesting

I've given up trying to deploy to servers directly from Eclipse as I do with other J2EE servers at this point in favor of using the websphere application toolkit v6.0.  

Have fun trying to get EAR files to deploy to WAS.  I'd love to hear from you if you do.

Are you using Eclipse, or Rational Application Developer (RAD)?

Are you asking about getting the Application on the AppServer?
If so, from Eclipse, or using the Application Server Toolkit (AST)?
If you are using Eclipse, which version?