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Can I use microsoft defrag on a server drive which contains BOTH data AND the exchange database

Last Modified: 2008-04-09
I need to defrag the only drive on the server which has both data and the exchange database.
The data needs it badly, I believe Exchange looks after itself.
Is it safe to use the microsoft defrag tool?
Should I stop the exchange service? Any other requirements?
( I back up Exchange using Arcserve to document level.)
Or what?

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