webprouk
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Compatibility of Windows 2003 64 Bit in a 32 bit enviroment
Is there any compatibility issues with putting a new Windows 2003 64 bit system into an existing Windows 2003 domain with servers running standard 32Bit?
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Printer drivers and software for other peripherals can be...challenging...if that's applicable to your environment.
Aside from that I haven't found anything specific to the Windows OS that causes issue, mostly compatibility with 3rd-party apps being compatible or not with the 64-bit architecture.