I have 2 mailboxed in Outlook 2007 - one is my main mailbox, the other is a shared "group mailbox". I have 2 signatures defined. One signature is the dafault signature that I use for my main mailbox. The other is a signature that I use when sending mail from the shared mailbox. Right now, I have to manually pick the appropriate signature for the shared mailbox any time I reply to mail in that mailbox or draft a new message from that mailbox. Is there a way to script this using a macro? Thanks.