I'm working with a several-month-old Dell desktop computer (Win XP Pro) where we've installed Adobe Creative Suite, primarily to use Photoshop and maybe Acrobat. After CS was installed in confusing circumstances, then uninstalled, and then reinstalled (with many complications along the way), I an now run most of the CS components--at any rate, they start up--namely InDesign, Acrobat, GoLive, and ImageReady.
But when I start Photoshop, it displays its first couple screens full of stuff (before there's any user input), and then displays a dialogue box saying, 'Could not initialize Photoshop failed to initialize CoolType'. When you click OK, Photoshop terminates.
It may or may not be relevant, but Illustrator also won't start, though it doesn't even give me the courtesy of an error message. It just displays that little box with the graphics and the list of developers, for 30 seconds or so, and then it disappears without a trace. That's not hugely important to us, as the user of this computer doesn't use Illustrator (yet); I mention it only as a possible clue to the Photoshop problem.