Exchange causing many 565 Failure Audits

I have an Exchange 2003 SP2 Server and I am seeing the below 565 Failure audit about every minute on our domain controller (2000 SP4) Any insight would be great

Event Type:      Failure Audit
Event Source:      Security
Event Category:      Directory Service Access
Event ID:      565
Date:            1/26/2008
Time:            12:58:00 PM
Computer:      DC1
Object Open:
       Object Server:      DS
       Object Type:      configuration
       Object Name:      CN=Configuration,DC=millworkone,DC=com
       New Handle ID:      -
       Operation ID:      {0,42477531}
       Process ID:      268
       Primary User Name:      DC1$
       Primary Domain:      MILLWORKONE
       Primary Logon ID:      (0x0,0x3E7)
       Client User Name:      EXCHANGE$
       Client Domain:      MILLWORKONE
       Client Logon ID:      (0x0,0x5AEB0)
       Accesses            Control Access
       Privileges            -

Read Property
Write Property
Delete Tree
List Object
Control Access
            Manage Replication Topology

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