Locking ISA Down

I currently have an ISA Server 2006 Enterprise Edition Installed with a single NIC. I am using it as a reverse proxy and a forward proxy. All of my develpoers are in the domain admins group within the domain so they are are able to log onto the ISA server. I need to all the developers to remain in the Domain Admins group but be denied from logging on to the ISA Box locally or through their domain credentials. I want only three users to be able to log onto the server. Not sure how i can accomplish this because the useres are members of the domain admins group.  
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If they are in the domain admins group the cannot be denied access to ISA Server.
What is the problem? Are they changing the configuration?
knabiticAuthor Commented:
Yes they are changing the config, i want to limit the changes to only a few people. On the ISA properties added a user that i wanted to have access to create and change rules and removed the local administrators group. This seemed to deny users that are Domain admins but i am not sure if i am missing somthing? Any ideas if that a viable solution?
Take the Doamins administrators group from the Local machine users and manually add the users you want.

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Microsoft Forefront ISA Server

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