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Create the DisableDynamicUpdate reg DWORD key and give it a value of 1 under the specific interface's name.
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Create the DisableDynamicUpdate reg DWORD key and give it a value of 1 under the specific interface's name.

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And that won't affect the other interfaces? &nbsp;I'm only concerned because this is the main Exchange server.
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And that won't affect the other interfaces?  I'm only concerned because this is the main Exchange server.

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No, &nbsp;that registry key forces you to recognize and change only the target nic.
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No,  that registry key forces you to recognize and change only the target nic.

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I did this rebooted and they still came back....
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I did this rebooted and they still came back....

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This server was a DNS server itself which I did not realize would make a difference. 
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This server was a DNS server itself which I did not realize would make a difference.

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I installed an additional NIC in one of my servers last night for a iSCSI connection. I assigned it IP addressed and made the mistake of not unchecking the Register in DNS box. I realized my mistake this morning and unchecked the box but the address keep reappearing in DNS. How do I block it or track where it is coming from. I have multiple DNS servers in each site. 
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I installed an additional NIC in one of my servers last night for a iSCSI connection. I assigned it IP addressed and made the mistake of not unchecking the Register in DNS box. I realized my mistake this morning and unchecked the box but the address keep reappearing in DNS. How do I block it or track where it is coming from. I have multiple DNS servers in each site. 

DNS record keeps reappearing

The Domain Name System (DNS) is a hierarchical, globally distributed system responsible for associating the name of a computer, service or other resource into an IP address for connecting to the Internet or a private network. Most prominently, it translates domain names to the numerical IP addresses needed for the purpose of computer services and devices worldwide.

Transmission Control Protocol/Internet Protocol (TCP/IP) is the set of networking protocols that define end-to-end connectivity specifying how data should be packeted, addressed, transmitted, routed and received at the destination. This functionality is organized into four abstraction layers which are used to sort all related protocols according to the scope of networking involved.

TCP/IP

Active Directory (AD) is a Microsoft brand for identity-related capabilities. In the on-premises world, Windows Server AD provides a set of identity capabilities and services, and is hugely popular (88% of Fortune 1000 and 95% of enterprises use AD). This topic includes all things Active Directory including DNS, Group Policy, DFS, troubleshooting, ADFS, and all other topics under the Microsoft AD and identity umbrella.