How to Check for a Null Value

I am trying to determine is a value is null using the below code:

       If Not myValue = "" And Not myValue = DBNull Then
                do stuff
       End If

But it errors and tells me that 'DBNull' is a type and cannot be used as an expression.
Can someone let me know the if statement i need to use to see is a value is not "" and not null
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Is the value in a database then when you "select data from table where value is null"
if you want if the value is null in a database, then use DBnull.Value

if you want if the value is null in the memory then use nothing

But nothing should be the first check
if myvalue isnot nothing and myValue <> "" then
   do stuff
end if

If Not myvalue Is Nothing AndAlso Not myvalue Is DBNull.Value Then
'It should work.

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Visual Basic.NET

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