It looks like I am getting spoofed. Noone from my domain is sending these messages. Is there a way to stop this?

I am getting an error - Source: MSExchangeTransport, Category: SMTP Protocol, Event ID: 7004 and Enent ID: 7002 every few seconds.  I don't think anyone in my organization is sending out emails to the recipients listed in the error description.  Is my exchange server getting spoofed?  Can I stop it?  Should I be worried.

Here is an example of the error 7004:

This is an SMTP protocol error log for virtual server ID 1, connection #3309. The remote host "216.92.127.212", responded to the SMTP command "rcpt" with "553 This server does not accept mail for that address (#5.7.1)  ". The full command sent was "RCPT TO:<LadonnapolytechnicBateman@medical-search.org>  ".  This will probably cause the connection to fail.

Here is an example of the warning 7002:

This is an SMTP protocol warning log for virtual server ID 1, connection #3310. The remote host "206.169.106.4", responded to the SMTP command "rcpt" with "450 4.1.1 <FranciscaskitHorner@lisp.org>: Recipient address rejected: User unknown in local recipient table  ". The full command sent was "RCPT TO:<FranciscaskitHorner@lisp.org>  ".  This may cause the connection to fail.

brendanosmithAsked:
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kieran_bCommented:
That is more likely to be NDR spam than spoofing, you can combat it with recipient filtering and tarpitting -> http://www.amset.info/exchange/filter-unknown.asp

Kieran
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brendanosmithAuthor Commented:
Thanks for your response.  Why would a remote host be responding that an address does not exist in my domain?  The email address mentioned in the error message is not our domain.  If the email address were @mydomain.com I would understand but my domain is neither  @medical-search.org, @lisp.org nor any other account mentioned in any other error.  If I don't understand this please explain.

Thanks
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kieran_bCommented:
>>Why would a remote host be responding that an address does not exist in my domain?

Where does it say that?  I can see it saying that the recipient address does not exist.

Here is what is happening;

"Spamming Monkey A" sends mail to sadlansiuhfiw@yourdomain.com pretending to be from target@someotherdomain.com

as sadlansiuhfiw@yourdomain.com is not a legitimate email address, your server dilligently tries to advise the sender that they got something wrong.  Unfortunately, the sender has been faked.  target@someotherdomain.com has just got the spam message, that "Spamming Monkey A" was always trying to send.
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brendanosmithAuthor Commented:
Thanks for the response.  I want to make sure that I am clear.  The message is stating that "Recipient address rejected: User unknown in local recipient table ".  However the domain of the email address mentioned in the message (FranciscaskitHorner@lisp.org) is not mine.  To put it another way...my domain is not lisp.org.  So it seems to me that the exchange server at lisp.org is sending a message to me saying that the user does not exist in their domain.  It appears as if the mail server at lisp.org thinks that someone from my domain sent the email.  That is why I thought we were getting spoofed.  
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kieran_bCommented:
You are being spoofed, in a way.  It is technically known as NDR spam, spoofing is slightly different, but your description above is accurate as to what is happening.
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brendanosmithAuthor Commented:
Thanks for all of the help!!!
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