Clickonce Crystal Reports XI Release 2 deploy to x64 machine errors

We have Clickonce application that has a prerequisite of Crystal Reports Release 2. It has worked fine on all our XP 32bit machine. Now deploying to a Vista x64 machine when one attempts to use the windows form app to run a report we get this error message:

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Crystal Reports XI Release 2
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An error has occurred while attempting to load the Crystal Reports runtime.

Either the Crystal Reports registry key permissions are insufficient or the Crystal Reports runtime is not installed correctly.

Please install the appropriate Crystal Reports redistributable (CRRedist*.msi) containing the correct version of the Crystal Reports runtime (x86, x64, or Itanium) required.  Please go to http://www.businessobjects.com/support for more information.
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OK  
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I have searched high and low for how to resolve this, but cannot. Any suggestions?

Thanks.