Will installing OS adding it to a domain installing all Applications through SCCm and adding the machine to another domain create any problems.

Hi,

Will installing OS adding it to a domain installing all Applications through SCCm and adding the machine to another domain create any problems.
My senario is like this....
I have a sepearte network where we install OS and all applications...For installing Applications i use SCCM. So the machine have to be in the Domain.
Will readding the machine to another domain be a problem?
What all will the changes be?

Regards
Sharath