I'm having problems sending Internet e-mail messages on a new e-mail server (exchange 2007). I'm getting the following error across all domains: 451 4.4.0 Primary target IP address responded with "421 4.2.1 Unable to connect." Attempted failover to alternate host, but that did not succeed. Either there are no alternate hosts or delivery failed to all alternate hosts."
This is a copy of the send log
2008-06-25T17:11:07.878Z,Internet,08CAA34AF86795A8,0,,18.104.22.168:25,*,,attempting to connect
2008-06-25T17:11:14.441Z,Internet,08CAA34AF86795A8,1,,22.214.171.124:25,*,,"Failed to connect. Error Code: 10061, Error Message: No connection could be made because the target machine actively refused it 126.96.36.199:25"
2008-06-25T17:11:14.441Z,Internet,08CAA34AF86795A8,0,,188.8.131.52:25,*,,attempting to connect
2008-06-25T17:11:20.894Z,Internet,08CAA34AF86795A8,1,,184.108.40.206:25,*,,"Failed to connect. Error Code: 10061, Error Message: No connection could be made because the target machine actively refused it 220.127.116.11:25"
2008-06-25T17:11:20.894Z,Internet,08CAA34AF86795A8,0,,18.104.22.168:25,*,,attempting to connect
2008-06-25T17:11:33.910Z,Internet,08CAA34AF86795A8,1,,22.214.171.124:25,*,,"Failed to connect. Error Code: 10060, Error Message: A connection attempt failed because the connected party did not properly respond after a period of time, or established connection failed because connected host has failed to respond 126.96.36.199:25"
I'm fairly new to Exchange 2007 and could use some guidance on this issue.