I have 2 drop down list poupulated from a datatable and a gridview populated from the datatable.onclicking submit button my values in the grid need to be changed based on selected index

I have two dropdownlists populated from a datatable and a gridview populated from a datatable.On clicking on the submit button i like to populate my grid values based on the selcted index of the dropdownlist.can any one help me.

<asp:DropDownList ID="DropDownList1" runat="server" SkinID="drpLarge" 
                        onselectedindexchanged="dd1PermissionProups_SelectedIndexChanged">
					  </asp:DropDownList>
					<asp:DropDownList ID="DropDownList2" runat="server" SkinID="drpLarge">
					    </asp:DropDownList>
					<asp:Button ID="Button1" runat="server" Text="Filter"  CssClass="filter-button"
                        FilterCssClass="filter-button" onclick="Filter_Click" />
				</div>
				<asp:GridView ID="GridView1" runat="server" AutoGenerateColumns="False" 
                    Width="1018px" BackColor="#DEBA84" BorderColor="#DEBA84" BorderStyle="None" 
                    BorderWidth="1px" CellPadding="3"  Height="399px" 
                    onselectedindexchanged="GridView1_SelectedIndexChanged" CellSpacing="2" 
                    AllowPaging="True" onrowediting="GridView1_RowEditing">
                        <PagerSettings Mode="NextPreviousFirstLast" />
                        <FooterStyle BackColor="#F7DFB5" ForeColor="#8C4510" />
                        <RowStyle BackColor="#FFF7E7" ForeColor="#8C4510" />
            <Columns>
            <asp:TemplateField HeaderText="Email1">
                    <ItemTemplate>
                        <asp:Label ID="Email1" runat="server" Text='<%# Eval("Email1") %>'></asp:Label>
                    </ItemTemplate>
                </asp:TemplateField>
                <asp:TemplateField HeaderText="PermissionGroup">
                    <ItemTemplate>
                        <asp:Label ID="PermissionGroup" runat="server" Text='<%# Eval("PermissionGroup") %>'></asp:Label>
                    </ItemTemplate>
                </asp:TemplateField>
                <asp:TemplateField HeaderText="Status">
                    <ItemTemplate>
                        <asp:Label ID="Status" runat="server" Text='<%# Eval("Status") %>'></asp:Label>
                    </ItemTemplate>
                </asp:TemplateField>                <asp:ButtonField ButtonType="Button" CommandName="Edit" Text="Button" />
                </Columns>
                </asp:GridView>

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