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Check this MS article. &nbsp;Without knowing more details I can't tell you the exact cause but this article should help.<br />
<a href="http://support.microsoft.com/?kbid=280823" rel="ugc">http://support.microsoft.com/?kbid=280823</a>&quot;%20rel=&quot;nofollow&quot;&gt;<a href="http://support.microsoft.com/?kbid=280823" rel="ugc">http://support.microsoft.com/?kbid=280823</a>
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No i didn't installed any updates .I simply intalled exchange server 2003 on windows server 2003 and configured it as front end.It was all going well and synchronising with backend exchange server 2003.Two days later I started to get this problem.If i go to browser and type in my backend exchange address as <a href="http://hmailsvr2/exchange" rel="ugc">http://hmailsvr2/exchange</a>&nbsp;it opens with owa page well and everything is fine but if i use my front end address as <a href="http://hmailsvrweb/exchange" rel="ugc">http://hmailsvrweb/exchange</a>&nbsp;owa opens but buttons don't work.kindly help me out
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I installed exchange server 2003 on one of virtual machines called hmailsvrweb and configured it as front end server.Already there is backend exchange as well called hmailsvr2.After designating hmailsvrweb as front end when i go to browser and type <a href="http://hmailsvrweb/exchange.it" rel="ugc">http://hmailsvrweb/exchange.it</a>&nbsp;displays with user name and pwd and authenticates and owa open.In owa i can't see anything when i press inbox,calender etc.meaning nothing happens when i click any of the buttons and owa displays loading message <br />
<a href="https://filedb.experts-exchange.com/incoming/2008/07_w29/42061/owa-error.bmp" target="_blank" class="file-inline" title="loading error in owa (2.9 MB)"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path d="M67.508 468.467c-58.005-58.013-58.016-151.92 0-209.943l225.011-225.04c44.643-44.645 117.279-44.645 161.92 0 44.743 44.749 44.753 117.186 0 161.944l-189.465 189.49c-31.41 31.413-82.518 31.412-113.926.001-31.479-31.482-31.49-82.453 0-113.944L311.51 110.491c4.687-4.687 12.286-4.687 16.972 0l16.967 16.971c4.685 4.686 4.685 12.283 0 16.969L184.983 304.917c-12.724 12.724-12.73 33.328 0 46.058 12.696 12.697 33.356 12.699 46.054-.001l189.465-189.489c25.987-25.989 25.994-68.06.001-94.056-25.931-25.934-68.119-25.932-94.049 0l-225.01 225.039c-39.249 39.252-39.258 102.795-.001 142.057 39.285 39.29 102.885 39.287 142.162-.028A739446.174 739446.174 0 0 1 439.497 238.49c4.686-4.687 12.282-4.684 16.969.004l16.967 16.971c4.685 4.686 4.689 12.279.004 16.965a755654.128 755654.128 0 0 0-195.881 195.996c-58.034 58.092-152.004 58.093-210.048.041z"/></svg>owa-error.bmp</a>
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owa-error.bmp

I installed exchange server 2003 on one of virtual machines called hmailsvrweb and configured it as front end server.Already there is backend exchange as well called hmailsvr2.After designating hmailsvrweb as front end when i go to browser and type http://hmailsvrweb/exchange.it displays with user name and pwd and authenticates and owa open.In owa i can't see anything when i press inbox,calender etc.meaning nothing happens when i click any of the buttons and owa displays loading message 

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Windows Server 2003 was based on Windows XP and was released in four editions: Web, Standard, Enterprise and Datacenter. It also had derivative versions for clusters, storage and Microsoft’s Small Business Server. Important upgrades included integrating Internet Information Services (IIS), improvements to Active Directory (AD) and Group Policy (GP), and the migration to Automated System Recovery (ASR).

Windows Server 2003

Exchange is the server side of a collaborative application product that is part of the Microsoft Server infrastructure. Exchange's major features include email, calendaring, contacts and tasks, support for mobile and web-based access to information, and support for data storage.